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Symbol
Name
ID
Insc
INSC spindle orientation adaptor protein
MGI:1917942
Phenotype annotations related to nervous system
Darker colors indicate more annotations

Mouse Phenotypes
seizures
abnormal radial glial cell morphology
abnormal neuronal precursor proliferation
abnormal cochlear hair cell morphology
abnormal cochlear hair cell stereociliary bundle morphology
abnormal brain development
abnormal cortical intermediate zone morphology
abnormal cortical plate morphology
thin cortical plate
decreased brain size
enlarged lateral ventricles
abnormal cerebral cortex morphology
abnormal stratification in cerebral cortex
thickened cerebral cortex
thin cerebral cortex
abnormal lateral ganglionic eminence morphology
abnormal neuron morphology
increased neuronal precursor cell number
decreased neuron number
increased neuron number
Availability Mouse Genotype
Insctm1.2Cayo/Insctm1.2Cayo
Gt(ROSA)26Sortm1.1(CAG-Insc/GFP)Jakn/Gt(ROSA)26Sor+
Gt(ROSA)26Sortm1(CAG-Bgeo,-Insc/GFP)Jakn/Gt(ROSA)26Sortm1(CAG-Bgeo,-Insc/GFP)Jakn
Tg(Nes-cre)1Wmz/0  (conditional)
Insctm1Jakn/Insctm1Jakn
Tg(Nes-cre)1Wmz/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory